邓正玉 特任研究员

电子邮件：zydeng@ustc.edu.cn

主　　页：https://zydeng1990.wixsite.com/deng-research-group

个人简历

2024/07至今，中国科大苏州高等研究院，特任研究员，博士生导师

2021/3-2024/06，加拿大西安大略大学 (University of Western Ontario)，博士后，导师：Elizabeth R. Gillies

2017/6-2019/09，湖南大学，博士后， 导师：谭蔚泓 院士

2011/09-2017/03，中国科学技术大学，博士，导师：刘世勇 教授

2007/09-2011/06，西北工业大学，本科

研究方向

智能生物材料

精密高分子

生物正交化学

近期代表性论文

1. Deng, Z.; Liang, X.; Gillies, E. R.* "Click to Self-immolation: A “Click” Functionalization Strategy towards Triggerable Self-Immolative Homopolymers and Block Copolymers", Angew. Chem. Int. Ed.2024, 63, e202317063 (Hot Paper).

2. Tan, J.^#; Deng, Z.^#; Song, C.; Xu J.; Zhang, Y.; Yu, Y.; Hu, J.*; Liu, S.* "Coordinating External and Built-In Triggers for Tunable Degradation of Polymeric Nanoparticles via Cycle Amplification", J. Am. Chem. Soc.2021, 143, 13738 (^#Equal first author).

3. Yang, Q.^#; Deng, Z.^#; Wang, D.; He, J.; Zhang, D.; Tan, Y.; Peng, T.; Wang, X. Q.*; Tan, W.* "Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect", J. Am. Chem. Soc.2020, 142, 2532 (^#Equal first author).

4. Deng, Z.; Yuan, S.; Xu, X. R.; Liang, H.; Liu, S.* "Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates", Angew. Chem. Int. Ed.2018, 57, 8896.

5. Deng, Z.; Qian, Y.; Yu, Y.; Liu, G.; Hu, J.; Zhang, G.; Liu, S.* "Engineering Intracellular Delivery Nanocarriers and Nanoreactors from Oxidation-Responsive Polymersomes via Synchronized Bilayer Cross-Linking and Permeabilizing Inside Live Cells", J. Am. Chem. Soc.2016, 138, 10452 (ESI Highly Cited Papers).

6. Deng, Z.; Gillies, E. R.* "Emerging Trends in the Chemistry of End-to-End Depolymerization", JACS Au2023, 3, 2436.

7. Shi, Q.^#; Deng, Z.^#; Hou, M.^#; Hu X.*; Liu S.* "Engineering precise sequence-defined polymers for advanced functions", Prog. Polym. Sci.2023, 141, 101677 (^#Equal first author).