刘固寰 理学博士

高分子科学与工程系

副研究员

Tel: 0551-63607579

E-mail: ghliu@

ResearcherID: K-8515-2013

个人简介

刘固寰，男，湖南长沙人。2008.7湘潭大学高分子材料与工程专业本科；2015.1中国科学技术大学高分子化学与物理专业博士，导师为刘世勇教授，博士论文入选中科院优秀博士论文。2015.2-2017.3，中国科学技术大学博士后；2017.4-2019.3中国科学技术大学特任副研究员。2019.3-至今，中国科学技术大学高分子科学与工程系副研究员。迄今已在SCI期刊发表论文29篇，以第一/通讯作者在J. Am. Chem. Soc., Angew. Chem. Int. Ed., Macromolecules等发表论文9篇。所有论文共被引1000余次，4篇论文(曾)入选ESI高被引论文，1篇论文被ACS选为Editors' Choice Article等。

研究兴趣与研究方向

1. 响应性程序降解聚合物

2. 耗散远离平衡态自组装

3. 活性、自适应和自主的分子系统

4. 化学与生物传感器、诊疗试剂

主要发表文章

1.G. H. Liu, G. H. Shi, H. Y. Sheng, Y. Y. Jiang, H. J. Liang, S. Y. Liu* 'Doubly Caged Linker for AND-Type Fluorogenic Construction of Protein/Antibody Bioconjugates and In Situ Quantification', Angewandte Chemie International Edition, 56, 8686-8691 (2017);

2.G. H. Liu, G. F. Zhang, J. M. Hu, X. R. Wang, M. Q. Zhu, S. Y. Liu* 'Hyperbranched Self-Immolative Polymers (hSIPs) for Programmed Payload Delivery and Ultrasensitive Detection', Journal of the American Chemical Society, 137, 11645-11655 (2015);

3.G. H. Liu, X. R. Wang, J. M. Hu, G. Y. Zhang, S. Y. Liu* 'Self-Immolative Polymersomes for High-Efficiency Triggered Release and Programmed Enzymatic Reactions', Journal of the American Chemical Society, 136, 7492-7497 (2014);

4.K. N. Zhu, Z. Y. Deng, G. H. Liu*, J. M. Hu*, S. Y. Liu* 'Photo-Regulated Cross-Linking of Superparamagnetic Iron Oxide Nanoparticle (SPION)-Loaded Hybrid Nanovectors with Synergistic Drug Release and Magnetic Resonance (MR) Imaging Enhancement', Macromolecules, 50, 1113-1125 (2017);

5.C. Z. Yao, X. R. Wang, G. H. Liu*, J. M. Hu*, S. Y. Liu* 'Distinct Morphological Transitions of Photo-Reactive and Thermo-Responsive Vesicles for Controlled Release and Nanoreactors', Macromolecules, 49, 8282-8295 (2016);

6.C. Wang, G. Y. Zhang, G. H. Liu*, J. M. Hu*, S. Y. Liu* 'Photo- and Thermo-Responsive Multicompartment Hydrogels for Synergistic Delivery of Gemcitabine and Doxorubicin', Journal of Controlled Release, 259, 149-159 (2017);

7.G. H. Liu, J. M. Hu, S. Y. Liu* 'Emerging Applications of Fluorogenic and Non-Fluorogenic Bifunctional Linkers', Chemistry-A European Journal, 24, in press (2018);

8.G. H. Liu, J. M. Hu, G. Y. Zhang, S. Y. Liu* 'Rationally Engineering Phototherapy Modules of Eosin-Conjugated Responsive Polymeric Nanocarriers via Intracellular Endocytic pH Gradients', Bioconjugate Chemistry, 26, 1328-1338 (2015);

9.G. H. Liu, H. Shi, Y. R. Cui, J. Y. Tong, Y. Zhao, D. J. Wang, Y. L. Cai* “Toward rapid aqueous RAFT polymerization of primary amine functional monomer under visible light irradiation at 25 °C”, Polymer Chemistry, 4, 1176-1182 (2013).