美国加利福利亚大学洛杉矶分校（UCLA）Gerard Wong 教授将应邀来访并于2016年7月15日 (本周五）下午2:00在微尺度理化大楼一楼科技展厅报告厅做学术报告。
报告题目：
Self-assembly and the immune system
报告摘要：
We present examples from our group where soft matter physics impacts unsolved problems in infectious diseases and auto-immune diseases. We will discuss how self-assembly impacts immune activation via both endosomal and cytosolic pathways, and how these pathways are at play in biological contexts (immune response in heart disease, necrotic cell death, neutrophil extracellular traps, autoimmune skin diseases). We will also discuss how machine learning can be used as an engine for not just finding known unknowns, such as new or better antimicrobial sequences, but also discovering unknown unknowns, such as new inter-relations in our existing taxonomies of innate immunity peptides.
报告题目：
Self-assembly and the immune system
报告摘要：
We present examples from our group where soft matter physics impacts unsolved problems in infectious diseases and auto-immune diseases. We will discuss how self-assembly impacts immune activation via both endosomal and cytosolic pathways, and how these pathways are at play in biological contexts (immune response in heart disease, necrotic cell death, neutrophil extracellular traps, autoimmune skin diseases). We will also discuss how machine learning can be used as an engine for not just finding known unknowns, such as new or better antimicrobial sequences, but also discovering unknown unknowns, such as new inter-relations in our existing taxonomies of innate immunity peptides.
Gerard C. L. Wong
Bioengineering Dept., Chemistry & Biochemistry Dept.,
California NanoSystems Institute
UCLA
Short Biography
Professor Wong received his BS degree in Physics from Caltech and his PhD in Physics from UC Berkeley. He subsequently pursued postdoctoral research on soft matter physics at the FOM Institute for Atomic and Molecular Physics in Amsterdam, and on biophysics and bioengineering at UC Santa Barbara. Dr. Wong represented the U.S. in the NSF-MEXT US-Japan Young Scientist Symposium on Nanobiotechnology (2005), the Taipei Academia Sinica International Workshop on Soft Matter and Biophysics (2007), and the NSF-DST US-India Nanoscience & Engineering Workshop (2008). Dr. Wong currently serves on the Editorial Board of Physical Review E. His awards and recognitions include Director of the Center for Early Bacterial Biofilm Studies of Human Frontiers Science Program (2013) and Fellow of the American Physical Society (2012). To date, Dr. Wong has published many research articles in high-impact journals including Science, Nature, Nature Materials, Nature Communications, PNAS, JACS, and PRL.
Bioengineering Dept., Chemistry & Biochemistry Dept.,
California NanoSystems Institute
UCLA
Short Biography
Professor Wong received his BS degree in Physics from Caltech and his PhD in Physics from UC Berkeley. He subsequently pursued postdoctoral research on soft matter physics at the FOM Institute for Atomic and Molecular Physics in Amsterdam, and on biophysics and bioengineering at UC Santa Barbara. Dr. Wong represented the U.S. in the NSF-MEXT US-Japan Young Scientist Symposium on Nanobiotechnology (2005), the Taipei Academia Sinica International Workshop on Soft Matter and Biophysics (2007), and the NSF-DST US-India Nanoscience & Engineering Workshop (2008). Dr. Wong currently serves on the Editorial Board of Physical Review E. His awards and recognitions include Director of the Center for Early Bacterial Biofilm Studies of Human Frontiers Science Program (2013) and Fellow of the American Physical Society (2012). To date, Dr. Wong has published many research articles in high-impact journals including Science, Nature, Nature Materials, Nature Communications, PNAS, JACS, and PRL.
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