胡进明理学博士 高分子科学与工程系 特任教授 Tel: +86-551-63607579 (Lab) E-mail: jmhu@ustc.edu.cn Webpage: http://staff.ustc.edu.cn/~jmhu |
个人简介
研究兴趣与研究方向
2. 环境响应性有机/无机杂化材料的制备与功能拓展
3. 响应性高分子药物与基因输运和控释载体
4. 响应性聚合物基化学与生物传感器、诊疗试剂
通讯/第一作者论文
1. L. Wang, G. H. Liu, X. R. Wang, J. M. Hu,* G. Y. Zhang,* S. Y. Liu* “Acid-Disintegratable Polymersomes of pH-Responsive Amphiphilic Diblock Copolymers for Intracellular Drug Delivery” Macromolecules 2015, 48, 7262–7272. Monthly Most Read Article.
2. J. M. Hu, X. Wang, Y. F. Qian, Y. Q. Yu,* Y. Y. Jiang, G. Y. Zhang, S. Y. Liu* “Cytoplasmic Reactive Cationic Amphiphiles for Efficient Intracellular Delivery and Self-Reporting Smart Release” Macromolecules, 2015, 48, 5959-5968.
3. J. M. Hu, M. R. Whittaker, S. H. Yu, J. F. Quinn,* T. P. Davis* “Nitric Oxide (NO)-Cleavable Biomimetic Thermoresponsive Double Hydrophilic Diblock Copolymer with Tunable LCST”, Macromolecules, 2015, 48, 3817-3824.
4. J. M. Hu, M. R. Whittaker, T. P. Davis*, J. F. Quinn* “Application of Heterocyclic Polymers in the Ratiometric Spectrophotometric Determination of Fluoride”, ACS Macro Letters, 2015, 4, 236-241.
5. S. D. Tian, G. H. Liu, X. R. Wang, T. Wu, J. X. Yang, X. D. Ye, G. Y. Zhang, J. M. Hu,* S. Y. Liu* “pH-Regulated Reversible Transition Between Polyion Complexes (PIC) and Hydrogen Bonding Complexes (HBC) with Tunable Aggregation-Induced Emission” ACS Applied Materials & Interfaces, 2015, in press.
6. J. M. Hu, M. R. Whittaker, Y. Li, J. F. Quinn,* T. P. Davis* “The use of endogenous gaseous molecules (NO and CO2) to regulate the self-assembly of a dual-responsive triblock copolymer”, Polymer Chemistry, 2015, 6, 2407-2415.
7. J. M. Hu, S. Y. Liu* “Supramolecular Assembly-Assisted Synthesis of Responsive Polymeric Materials with Controlled Chain Topologies”, Macromolecular Chemistry and Physics, 2015, 216, 591-604. Chosen as one of 'Best of Macromolecular Journals, Edition 2016'. Yearly Most-accessed Article as of Oct, 2014-Sep, 2015.
8. J. M. Hu, S. Y. Liu* “Engineering Responsive Polymer Building Blocks with Host-Guest Molecular Recognition for Functional Applications”, Accounts of Chemical Research, 2014, 47, 2084-2095. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.
9. J. M. Hu, G. Y. Zhang, Z. S. Ge, S. Y. Liu* “Stimuli-Responsive Tertiary Amine Methacrylate-Based Block Copolymers: Synthesis, Supramolecular Self-Assembly and Functional Applications”, Progress in Polymer Science, 2014, 39, 1096–1143. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.
10. J. M. Hu, M. R. Whittaker, H. Doung, Y. Li, C. Boyer,*T. P. Davis* “Biomimetic Polymers Responsive to a Biological Signaling Molecule: Nitric Oxide (NO) Triggered Reversible Self-assembly of Single Macromolecular Chains into Nanoparticles”, Angewandte Chemie International Edition , 2014, 53, 7779–7784.
11. J. M. Hu, G. H. Liu, T. Liu, C. Wang, G. Y. Zhang, S. Y. Liu* “Spatiotemporal Monitoring Endocytic and Cytosolic pH Gradients with Endosomal Escaping pH-Responsive Micellar Nanocarriers”, Biomacromolecules, 2014, 15, 4293-4301.
12. X. L. Hu, J. M. Hu*, J. Tian, Z. S. Ge, G. Y. Zhang, K. F. Luo, S. Y. Liu* 'Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking and Drug Delivery', Journal of the American Chemical Society, 2013, 135, 17617–17629. Highlighted by Science-Business eXchange doi:10.1038/scibx.2013.1366; Hot Papers by Essential Science Indicators at ISI Web of Knowledge. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.
13. Y. Li, T. Liu, Y. F. Qian, G. Y. Zhang, J. M. Hu,* and S. Y. Liu* “Asymmetrically Functionalized β-Cyclodextrin-Based Star Copolymers for Integrated Gene Delivery and Magnetic Resonance Imaging Contrast Enhancement”, Polymer Chemistry, 2013, 5, 1743-1750.
14. J. M. Hu, T. Liu, G. Y. Zhang, F. Jin*, S. Y. Liu* “Synergistically Enhance Magnetic Resonance/Fluorescence Imaging Performance of Responsive Polymeric Nanoparticles under Mildly Acidic Biological Milieu”, Macromolecular Rapid Communications, 2013, 34, 749-758.
15. J. M. Hu, G. Q. Zhang*, S. Y. Liu* “Enzyme-Responsive Polymeric Assemblies, Nanoparticles and Hydrogels”, Chemical Society Reviews, 2012, 41, 5933-5949. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.
16. J. M. Hu, T. Wu, G. Y. Zhang, S. Y. Liu* 'Efficient Synthesis of Single Gold Nanoparticle Hybrid Amphiphilic Triblock Copolymers and Their Controlled Self-Assembly', Journal of the American Chemical Society, 2012, 134, 7624–7627.
17. J. M. Hu, T. Wu, G. Q. Zhang*, S. Y. Liu* “Highly Selective Fluorescence Sensing of Mercury Ions over a Broad Concentration Range Based on Mixed Polymeric Micelles”, Macromolecules, 2012, 45, 3939–3947.
18. J. M. Hu, Y. F. Qian,* X. F. Wang, T. Liu, S. Y. Liu* “Drug-Loaded and Superparamagnetic Iron Oxide Nanoparticle Surface Embedded Amphiphilic Block Copolymer Micelles for Integrated Chemotherapeutic Drug Delivery and MR Imaging”, Langmuir, 2012, 28, 2073-2082.
19. J. M. Hu, G.Y. Zhang, Y. H. Geng*, S. Y. Liu* “Micellar Nanoparticles of Coil-Rod-Coil Triblock Copolymers for Highly Sensitive and Ratiometric Fluorescent Detection of Fluoride Ions”, Macromolecules, 2011, 44, 8207–8214.
20. J. M. Hu, L. Dai, S. Y. Liu* “Analyte-Reactive Amphiphilic Thermoresponsive Diblock Copolymer Micelles-Based Multifunctional Ratiometric Fluorescent Chemosensors”, Macromolecules, 2011, 44, 4699-4710.
21. J. M. Hu, X. Z. Zhang, D. Wang, X. L. Hu, T. Liu, G. Y. Zhang*, S. Y. Liu* “Ultrasensitive Ratiometric Fluorescent pH and Temperature Probes Constructed from Dye-Labeled Thermoresponsive Double Hydrophilic Block Copolymers”, Journal of Materials Chemistry, 2011, 21, 19030-19038.
22. J. M. Hu, C. H. Li, Y. Cui, S. Y. Liu* “Highly Selective Colorimetric and Fluorometric Probes for Fluoride Ions Based on Nitrobenzofurazan-Containing Polymers”, Macromolecular Rapid Communications, 2011, 32, 610-615.
23. J. M. Hu, S. Y. Liu* “Responsive Polymers for Detection and Sensing Applications: Current Status and Future Developments”, Macromolecules, 2010, 43, 8315-8330. (Perspective Article, 国内首篇). Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge; Most Read Articles over the last 12 months during the period of Dec 2010-Dec 2011; Ranked 6th among Top 20 Most-Cited Article in Macromolecules Journal over the Past 3 years, as of April 2012.
24. J. M. Hu, Z. S. Ge,* Y. M. Zhou, Y. F. Zhang, S. Y. Liu* “Unique Thermo-Induced Sequential Gel-Sol-Gel Transition of Responsive Multiblock Copolymer-Based Hydrogels”, Macromolecules, 2010, 43, 5184–5187.
25. J. M. Hu, C. H. Li, S. Y. Liu* “Hg(II)-Reactive Double Hydrophilic Block Copolymer Assemblies as Novel Multifunctional Fluorescent Probes with Improved Performance”, Langmuir, 2010, 26, 724–729.
26. J. M. Hu, D. Wang, J. Xu, Z. Y. Zhu, S. Y. Liu* “Contraction and Collapsing Kinetics of Single Synthetic Polymer Chains at Small Quench Depths”, Macromolecular Chemistry and Physics, 2010, 211, 2573-2584.