报告人和单位

 Prof. Dr. Jong Seung Kim

 Department of Chemistry (College of Science)

Korea University

报告题目

Small Molecules Based Molecular Theranostics

报告时间

2016年1月13日 (星期三) 上午10:00

报告地点

环境资源楼939会议室

报告人

简介

Research Areas:

　　 Host-Guest Chemistry, Calixarene Chemistry

　　 Synthesis of Calix[4]arene crown ethers for selective separation of radioactive species

　　 N-Pivot Calix[4]azacrown ethers and Their Practical Applications

　　 Fluoresence sensors

　　 Studies on Alzheimer’s disease

　　 Development of new contrast agents for MRI

　　 Small molecule based drug delivery system

Selected Publications:

　　 M. H. Lee, J. L. Sessler, J. S. Kim, ‘Disulfide-Based Multifunctional Conjugates for Targeted Theranostic Drug Delivery’ Acc. Chem. Res. 2935-2946,48,2015.

　　 H. S. Jung, J. Han, J.-H. Lee, J. H. Lee, J.-M. Choi, H.-S. Kweon, J. H. Han, J. H. Kim, K. M. Byun, J. H. Jung, C. Kang, J. S. Kim, ‘Enhanced NIR Radiation-Triggered Hyperthermia by Mitochondrial Targeting’ J. Am. Chem. Soc. 3017−3023, 137, 2015.

　　 J. Wu, B. Kwon, W. Liu, E. Ansyln, P. Wang, J. S. Kim, "Chromogenic/Fluorogenic Ensemble Chemosensing System" Chem. Rev. 7893-7943, 115, 2015.

　　 M. H. Lee, J. S. Kim, J. L. Sessler, ‘Small molecule-based ratiometric fluorescence probes for cations, anions, and biomolecules’ Chem. Soc. Rev. 4185-4191, 44, 2015.

　 P. Verwilst, S. Park, B. Yoon, J. S. Kim, ‘Recent advances in Gd-chelate based bimodal optical/MRI contrast agents’ Chem. Soc. Rev. 1791-1806, 44, 2015. 6.　　 R. Kumar, J. Y. Han, H. J. Lim, W. X. Ren, Y. Lim, J. H. Kim, J. S. Kim, ‘Mitochondrial Induced and Self-Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment‘ J. Am. Chem. Soc. 17836-17843, 136, 2014.

　　 M. H. Lee, H. M. Jeon, J. H. Han, N. Park, C. Kang, J. L. Sessler, J. S. Kim, ‘Towards A Chemical Marker for Inflammatory Disease: A Fluorescent Probe for Membrane-Localized Thioredoxin’ J. Am. Chem. Soc. 8430-8437, 136, 2014.

　 M. H. Lee, N. Park, C. Yi, J. H. Han, J. Hong, K. P. Kim, D. H. Kang, J. L. Sessler, C. Kang, J. S. Kim, ‘Mitochondria-immobilized pH-Sensitive Off-On Fluorescent Probe’ J. Am. Chem. Soc. 14136-14142, 136, 2014. 9.　　 E.-J. Kim, S. Bhuniya, H. Lee, H. M. Kim, C. Cheong, S. Maiti, K. S. Hong, J. S. Kim, ‘An Activatable Prodrug for the Treatment of Metastatic Tumor’ J. Am. Chem. Soc. 13888-13894, 136, 2014.

10.S. Bhuniya, S. Maiti, E.-J. Kim, H. Lee, J. L. Sessler, K. S. Hong, J. S. Kim, ‘An Activatable Theranostic for Targeted Cancer Therapy and Imaging’ Angew. Chem. Int. Ed. 4469-4474, 53, 2014.