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阳丽华理学博士 高分子科学与工程系 副教授 博士生导师 Tel: +86-551-63606960 (Lab) 主页：http://staff.ustc.edu.cn/~lhyang E-mail: lhyang@ustc.edu.cn |
教 育
University of Illinois at Urbana-Champaign 获得学位时间
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博士学位 （专业：材料科学与工程） 2008年05月
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硕士学位 （专业：材料科学与工程） 2003年12月
中国科学技术大学
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学士学位 （专业：材料科学与工程） 2002年07月
工作经历
中国科学技术大学 (2011年–至今)
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材料科学与工程系 副教授 博导
四川大学 (2008年 – 2011年)
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化学工程学院 副教授 博导
University of Illinois at Urbana-Champaign (2002年 – 2008年)
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材料科学与工程系 研究生研究助理、教学助理
获奖与荣誉
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四川省学术与技术带头人后备人选（2010）
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Racheff-Intel Award for Graduate Research, Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign (2007)
研究兴趣
生物材料, 仿生系统, 生物物理, 药物输送，纳米颗粒
代表学术论文（* 通讯作者）
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Lihua Yang, Hongjun Liang, Thomas E. Angelini, John Butler, Robert Coridan, Jay X. Tang, Gerard C.L. Wong*, “Self-assembled virus-membrane complexes”, Nat. Mater., 2004, 3(9), 615-619
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Lihua Yang, Vernita D. Gordon, Abhijit Mishra, Abhigyan Som, Kirstin R. Purdy, Matthew A. Davis, Gregory N. Tew*, Gerard C.L. Wong*, “Synthetic antimicrobial oligomers induce composition-dependent topological transition in membranes”, J. Am. Chem. Soc., 2007, 129, 12141-12147
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Lihua Yang, Vernita D. Gordon, Dallas R. Trinkle, Nathan W. Schmidt, Mathew A. Davis, Clarabelle DeVries, Abhigyan Som, John E. Cronan, Jr., Gregory N. Tew, Gerard C. L. Wong*, “Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via negative curvature lipid targeting”, Proc. Natl. Acad. Sci. U.S.A., 2008, 105, 20595-20600
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Abhijit Mishra, Vernita D. Gordon, Lihua Yang, Robert Coridan, Gerard C. L. Wong*, “HIV TAT domain induces 6nm pores in membranes”, Angew. Chem. Int. Ed., 2008, 47, 2986-2989
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Abhigyan Som, Lihua Yang, Gerard C. L. Wong*, Gregory N. Tew*, “Divalent Metal Ion Triggered Activity of A Synthetic Antimicrobial in Cardiolipin Membranes”, J. Am. Chem. Soc., 2009, 131, 15102-15103
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Kan Hu, Nathan W. Schmidt, Rui Zhu, Yunjiang Jiang, Ghee Hwee Lai, Gang Wei, Edmund F. Palermo, Kenichi Kuroda*, Gerard C. L. Wong*, Lihua Yang*, “A Critical Evaluation of Random Copolymer Mimesis of Homogeneous Antimicrobial Peptides”, Macromolecules, 2013, 46, (5), 1908-1915
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Yunjiang Jiang, Xin Yang, Rui Zhu, Kan Hu, Wang-Wei Lan, Fang Wu, Lihua Yang*, “Acid-Activated Antimicrobial Random Copolymers: A Mechanism-Guided Design of Antimicrobial Peptide Mimics”, Macromolecules, 2013, 46, 3959−3964
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Liwei Hui, Ji-Gang Piao, Jeffrey Auletta, Kan Hu, Yanwu Zhu, Tara Meyer, Haitao Liu*, Lihua Yang*, “Availability of the Basal Planes of Graphene Oxide Determines Whether It Is Antibacterial”, ACS Appl. Mater. Interfaces, 2014, 6(15), 13183–13190
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Xin Yang, Kan Hu, Guantai Hu, Danyao Shi, Yunjiang Jiang, Liwei Hui, Rui Zhu, Yuntao Xie, Lihua Yang*, “Long Hydrophilic-and-Cationic Polymers: A Different Pathway toward Preferential Activity against Bacterial over Mammalian Membranes”, Biomacromolecules, 2014, 15(9), 3267–3277
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Ji-Gang Piao, Limin Wang, Feng Gao, Ye-Zi You*, Yujie Xiong*, Lihua Yang*, “Erythrocyte Membrane Is an Alternative Coating to Polyethylene Glycol for Prolonging the Circulation Lifetime of Gold Nanocages for Photothermal Therapy”, ACS Nano, in press
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