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BIOGRAPHICAL SKETCH | ||||
NAME Peng, Fangyu |
POSITION TITLE Associate Professor
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EDUCATION/TRAINING | ||||
INSTITUTION AND LOCATION |
DEGREE |
YEAR(s) |
FIELD OF STUDY | |
Jiangxi Medical College, Jiangxi, China |
M.D. |
1982 |
Medicine | |
University of South Florida, Tampa, FL |
Ph.D. |
1994 |
Mol Viral Oncology | |
University of Connecticut, Farmington, CT |
Residency |
2000 |
Nuclear Medicine | |
Clinical Center, NIH, Bethesda, MA |
Fellowship |
2003 |
Mol Imaging and | |
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Nuclear Medicine |
A. Positions and Honors.
Positions and Employment
1983 – 1984 Assistant Instructor, Ganan Medical College, Ganzhou, China
1985 – 1987 MS student, Institute of Virology, Chinese Academy of Preventive Medicine, Beijing, China
1988 – 1989 Research Associate, Cancer Institute, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, China
1994- 1995 Postdoctoral fellow, College of Surgeons and Physicians, Columbia University, New York, USA
1995 -1996 Research Fellow, Ball Memorial Hospital, Muncie, IN
1996 -1998 Resident Physician in Clinical Pathology, Upstate Med Univ., SUNY at Syracuse, NY
1998 - 2000 Resident Physician in Nuclear Medicine, Department of Diagnostic Imaging and Therapeutics, University of Connecticut Health Center, Farmington, CT
2000 - 2002 Resident Physician in Anatomic Pathology, Hartford Hospital, Hartford, CT
2002 - 2003 Clinical Fellow, Imaging Science Program, Clinical Center, NIH, Bethesda, MD
2003 - 2008 Assistant Professor of Pediatrics and Radiology
Staff Physician, PET Center, Detroit Medical Center
Member, Barbara Ann Karmanos Cancer Institute
School of Medicine, Wayne State University, Detroit, Michigan
2008 - Present Associate Professor, Department of Radiology
Associate Professor, Advanced Imaging Research Center
Director of PET Translational Imaging
Member, Harold C. Simmons Comprehensive Cancer Center
UT Southwestern Medical Center at Dallas, Texas
Other Experience and Professional Membership
1999 - 2000 Chief Resident in Nuclear Medicine, University of Connecticut Health Center, Farmington, CT
1998 - Present Member, Society of Nuclear Medicine
2000 - Present Diplomate, American Board of Pathology (CP)
2002 - Present Diplomate, American Board of Nuclear Medicine
2002 - Present Member, Academy of Molecular Imaging
2005 - Present Member, American Association for Cancer Research
B. Selected peer-reviewed publications, in chronological order (earliest to recent).
1. Peng F, Zhang Y, Xu Z, Qu F. Antiviral activity and Enhancement of Natural Killer Cell Cytotoxicity by extract of Lagenaria Siceraria Sprout. J. Clinical and Experimental Virology (Chinese) 1988; 2:47-49.
2. Peng F, Bradley G, Lancz G, Tanaka A, Nonoyama M. Isolation and characterization of cDNAs from BamHI-H Gene Family Transcripts Associated with the Tumorigenicity of the Marek's Disease Virus. Journal of Virology 1992;66(12):7389-7396.
3. Peng F, Specter S, Donovan J, Tanaka A, Nonoyama M. Prolonged Proliferation of Primary Chicken Embryo Fibroblasts Transfected with cDNAs from BamHI-H Gene Family of Marek's Disease Virus. International Journal of Oncology 1993; 3:587-591.
4. Makimura K, Peng F, Tsuji M, Hasegawa S, Kawai Y, Nonoyama M, Tanaka A. Mapping of Marek's Disease Virus Genome: Identification of Junction Sequences between Unique and Inverted Repeat Regions. Virus Genes 1994; 8:15-24.
5. Peng, F., Specter, S., Tanaka, A. and Nonoyama, M. BHa gene product of BamHI-H gene family of Marek's disease virus is made both in productively and latently infected cells. Int. J. Oncology 4: 799-802, 1994.
6. Peng F, Triplett D, Barna L. Direct PCR of Leukocytes Treated with Microwave Irradiation to Detect Factor V Leiden Mutation. Thrombosis Research 1996; 82(2):193-197.
7. Peng F, Triplett D, Barna L, Morrical D. Pulmonary Embolism and Premature Labor in a Patient with both Factor V Leiden and Methylenetetrahydrofolate Reductase C677T Mutation. Thrombosis Research 1996; 83(3):243-251.
8. Hoagland LE, Triplett DA, Peng F, L. Barna L. APC-rsistance as measured by a textarin time assay: Comparison to the APTT-based method. Thrombosis Research 1996; 83(5):363-373.
9. Vento JA, Peng F, Spencer RP, Ramsey WH. Massive and widely distributed splenosis. Clinical Nuclear Medicine, 1999; 24:845-846.
10. Peng F, Labelle LA, Rainey B, Tsongalis GJ. Single nucleotide polymorphism in the methylenetetrahydrofolate reductase gene are common in US Caucasian and Hispanic American Populations. International Journal of Molecular Medicine, 2001; 8:509-511.
11. Chen D, Peng F, Cui QC, Daniel KG, Orlu S, Liu J, Dou QP. Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis. Front Biosci 2005; 10:2932-2939. PMID: 15970547
12. Peng F, Liu J, Wu J-S, Lu X, Muzik O. Mouse Extra-hepatic Hepatoma Detected on microPET using Copper (II)-64 Chloride uptake Mediated by Endogenous Mouse Copper Transporter 1 Molecular Imaging and Biology, 2005; 7:325-329. PMID: 16220354
13. Peng F, Rabkin G, Muzik O. Use of 2-deoxy-2-[F-18]-fluoro-D-glucose Positron Emission Tomography to Monitor Therapeutic Response by Rhabdomyosarcoma in Children: Report of a Retrospective Case Study. Clinical Nuclear Medicine 2006; 31:394-397. PMID:16785806
14. Shakya R, Peng F*, Liu J, Heeg MJ, Verani CN*. Synthesis, Structure, and Anticancer Activity of Gallium(III) Complexes with Asymmetric Tridentate Ligands: Growth Inhibition and Apoptosis Induction of Cisplatin-resistant Neuroblastoma Cells. Inorganic Chemistry 2006; 45: 6263-6268. PMID: 16878935 *-Co-corresponding author.
15. Peng F, Lu X, Janisse J, Muzik O, Shields AF. Positron Emission Tomography of Human Prostate Cancer Xenografts in Mice with Increased Uptake of Copper (II)-64 Chlorides J. Nucl Med 2006; 47 (10): 1649-1652. PMID: 17015901
16. Yuan J, You Y, Lu X, Muzik O, Oupicky D, Peng F. Synthesis and Characterization of Poly(APMA)-DOTA-Copper Conjugate for Interventional Radionuclide Cancer Therapy: Assessment of Intratumoral Retention by microPET Imaging. Molecular Imaging 2007; 6(1): 10- 17. PMID:17311761
17. Peng F,Juhasz C, Bhambhani K, Wu D, Chugani DC, Chugani HT. Assessment of Progression and Treatment Response of Optic Pathway Glioma with Positron Emission Tomography using α-[11C]-methyl-L-tryptophan Molecular Imaging and Biology, 2007; 9(3): 106-109. PMID: 17318667
18. Zhang H, Thomas R, Oupicky D, Peng F.Synthesis and characterization of new copper thiosemicarbazone complexes with an ONNS quadridentate system: cell growth inhibition, S-phase cell cycle arrest and proapoptotic activities on the cisplatin-resistant neuroblastoma cells. Journal of Biological Inorganic Chemistry, 2008; 13(1):47-55. PMID: 17909866
19. Zhang H, Wu J-S, Peng F. Potent Anticancer Activity of Pyrrolidine Dithiocarbamate-Copper Complex against Cisplatin-resistant Neuroblastoma Cells. Anti-cancer Drugs, 2008; 19(2):125-132. PMID: 18176108
20. Rodriguez VR, Joshi A, Peng F, Rabah RM, Stockmann PT, Savaşan S. Positron emission tomography in subcutaneous panniculitis-like T-cell lymphoma. Pediatr Blood Cancer. 2009;52:406–408. PMID: 18985722
21. Juhász C, Muzik O, Lu X, Jahania MS, Soubani AO, Khalaf M, Peng F, Mangner TJ, Chakraborty PK, Chugani DC. Quantification of tryptophan transport and metabolism in lung tumors using positron emission tomography. J. Nucl Med, 2009; 50(3): 356-363. PMID: 19223408
22. Peng, F, Lutsenko S, Sun X, Muzik O. Positron Emission Tomography of Copper Metabolism in the Atp7b -/- Knock-out Mouse Model of Wilson’s Disease. Mol Imaging and Biology, 2011, Epub ahead of print. DOI: 10.1007/s11307-011-0476-4 PMID: 21327972.
23. Zhang, H, Cai, H., Lu, X, Muzik, O., Peng, F. Positron Emission Tomography of Human Hepatocellular Carcinoma Xenografts in Mice using Copper (II)-64 Chloride as a tracer. Academic Radiology, 2011 (In press)
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