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Peng Fangyu教授报告(09-13)
发布人: 发布时间:2011-09-13 浏览次数:63
     美国西南医学中心的Peng Fangyu教授于13日10:00在材料楼五楼会议室,做“Translational Research of Copper in Medicine:  Potentials for Diagnostic Imaging and Personalized Therapy”的报告,会议由尤业字老师主持,白如科、张国庆、梁高林、刘和文等教授以及研究生参加会议。

 
 
 
Peng Fangyu
 
 

 

BIOGRAPHICAL SKETCH

NAME

Peng, Fangyu

POSITION TITLE

Associate Professor

 

EDUCATION/TRAINING

INSTITUTION AND LOCATION

DEGREE

YEAR(s)

FIELD OF STUDY

Jiangxi Medical College, Jiangxi, China

M.D.

1982

Medicine

University of South Florida, Tampa, FL

Ph.D.

1994

Mol Viral Oncology

University of Connecticut, Farmington, CT

Residency

2000

Nuclear Medicine

Clinical Center, NIH, Bethesda, MA

Fellowship

2003

Mol Imaging and

 

 

 

Nuclear Medicine

 

A.  Positions and Honors.

Positions and Employment

1983 – 1984 Assistant Instructor, Ganan Medical College, Ganzhou, China

1985 – 1987      MS student, Institute of Virology, Chinese Academy of Preventive Medicine, Beijing, China

1988 – 1989      Research Associate, Cancer Institute, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, China

1994- 1995       Postdoctoral fellow, College of Surgeons and Physicians, Columbia University, New York, USA

1995 -1996       Research Fellow, Ball Memorial Hospital, Muncie, IN

1996 -1998       Resident Physician in Clinical Pathology, Upstate Med Univ., SUNY at Syracuse, NY

1998 - 2000      Resident Physician in Nuclear Medicine, Department of Diagnostic Imaging and Therapeutics, University of Connecticut Health Center, Farmington, CT

2000 - 2002      Resident Physician in Anatomic Pathology, Hartford Hospital, Hartford, CT

2002 - 2003      Clinical Fellow, Imaging Science Program, Clinical Center, NIH, Bethesda, MD

2003 - 2008      Assistant Professor of Pediatrics and Radiology

                Staff Physician, PET Center, Detroit Medical Center

                Member, Barbara Ann Karmanos Cancer Institute

                School of Medicine, Wayne State University, Detroit, Michigan

 2008 - Present   Associate Professor, Department of Radiology

                Associate Professor, Advanced Imaging Research Center

                Director of PET Translational Imaging

                Member, Harold C. Simmons Comprehensive Cancer Center

                UT Southwestern Medical Center at Dallas, Texas

 

Other Experience and Professional Membership

 

1999 - 2000      Chief Resident in Nuclear Medicine, University of Connecticut Health Center,  Farmington, CT

1998 - Present    Member, Society of Nuclear Medicine

2000 - Present    Diplomate, American Board of Pathology (CP)

2002 - Present    Diplomate, American Board of Nuclear Medicine                            

2002 - Present    Member, Academy of Molecular Imaging

2005 - Present    Member, American Association for Cancer Research

 

B.  Selected peer-reviewed publications, in chronological order (earliest to recent).

 

1.   Peng F, Zhang Y, Xu Z, Qu F. Antiviral activity and Enhancement of Natural Killer Cell Cytotoxicity by extract of Lagenaria Siceraria Sprout. J. Clinical and Experimental Virology (Chinese) 1988; 2:47-49.

2.   Peng F, Bradley G, Lancz G, Tanaka A, Nonoyama M. Isolation and characterization of cDNAs from BamHI-H Gene Family Transcripts Associated with the Tumorigenicity of the Marek's Disease Virus. Journal of Virology 1992;66(12):7389-7396.

3.   Peng F, Specter S, Donovan J, Tanaka A, Nonoyama M. Prolonged Proliferation of Primary Chicken Embryo Fibroblasts Transfected with cDNAs from BamHI-H Gene Family of Marek's Disease Virus. International Journal of Oncology 1993; 3:587-591.

4.   Makimura K, Peng F, Tsuji M, Hasegawa S, Kawai Y, Nonoyama M, Tanaka A. Mapping of Marek's Disease Virus Genome: Identification of Junction Sequences between Unique and Inverted Repeat Regions. Virus Genes 1994; 8:15-24.

5.   Peng, F., Specter, S., Tanaka, A. and Nonoyama, M. BHa gene product of BamHI-H gene family of Marek's disease virus is made both in productively and latently infected cells. Int. J. Oncology 4: 799-802, 1994.

6.   Peng F, Triplett D, Barna L. Direct PCR of Leukocytes Treated with Microwave Irradiation to Detect Factor V Leiden Mutation. Thrombosis Research 1996; 82(2):193-197.

7.   Peng F, Triplett D, Barna L, Morrical D.  Pulmonary Embolism and Premature Labor in a Patient with both Factor V Leiden and Methylenetetrahydrofolate Reductase C677T Mutation. Thrombosis Research 1996; 83(3):243-251.

8.   Hoagland LE, Triplett DA, Peng F, L. Barna L. APC-rsistance as measured by a textarin time assay: Comparison to the APTT-based method. Thrombosis Research 1996; 83(5):363-373.

9.   Vento JA, Peng F, Spencer RP, Ramsey WH. Massive and widely distributed splenosis. Clinical Nuclear Medicine, 1999; 24:845-846.

10. Peng F, Labelle LA, Rainey B, Tsongalis GJ. Single nucleotide polymorphism in the methylenetetrahydrofolate reductase gene are common in US Caucasian and Hispanic American Populations. International Journal of Molecular Medicine, 2001; 8:509-511.

11. Chen D, Peng F, Cui QC, Daniel KG, Orlu S, Liu J, Dou QP. Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis. Front Biosci 2005; 10:2932-2939. PMID: 15970547

12. Peng F, Liu J, Wu J-S, Lu X, Muzik O. Mouse Extra-hepatic Hepatoma Detected on microPET using Copper (II)-64 Chloride uptake Mediated by Endogenous Mouse Copper Transporter 1 Molecular Imaging and Biology, 2005; 7:325-329. PMID: 16220354

13. Peng F, Rabkin G, Muzik O. Use of 2-deoxy-2-[F-18]-fluoro-D-glucose Positron Emission Tomography to Monitor Therapeutic Response by Rhabdomyosarcoma in Children: Report of a Retrospective Case Study. Clinical Nuclear Medicine 2006; 31:394-397. PMID:16785806

14. Shakya R, Peng F*, Liu J, Heeg MJ, Verani CN*. Synthesis, Structure, and Anticancer Activity of Gallium(III) Complexes with Asymmetric Tridentate Ligands: Growth Inhibition and Apoptosis Induction of Cisplatin-resistant Neuroblastoma Cells. Inorganic Chemistry 2006; 45: 6263-6268. PMID: 16878935 *-Co-corresponding author.

15. Peng F, Lu X, Janisse J, Muzik O, Shields AF. Positron Emission Tomography of Human Prostate Cancer Xenografts in Mice with Increased Uptake of Copper (II)-64 Chlorides J. Nucl Med 2006; 47 (10): 1649-1652. PMID: 17015901

16. Yuan J, You Y, Lu X, Muzik O, Oupicky D, Peng F. Synthesis and Characterization of Poly(APMA)-DOTA-Copper Conjugate for Interventional Radionuclide Cancer Therapy: Assessment of Intratumoral Retention by microPET Imaging.  Molecular Imaging  2007; 6(1): 10- 17. PMID:17311761

17. Peng F,Juhasz C, Bhambhani K, Wu D, Chugani DC, Chugani HT. Assessment of Progression and Treatment Response of Optic Pathway Glioma with Positron Emission Tomography using α-[11C]-methyl-L-tryptophan Molecular Imaging and Biology, 2007; 9(3): 106-109. PMID: 17318667

18. Zhang H, Thomas R, Oupicky D, Peng F.Synthesis and characterization of new copper thiosemicarbazone complexes with an ONNS quadridentate system: cell growth inhibition, S-phase cell cycle arrest and proapoptotic activities on the cisplatin-resistant neuroblastoma cells. Journal of Biological Inorganic Chemistry, 2008; 13(1):47-55. PMID: 17909866

19. Zhang H, Wu J-S, Peng F. Potent Anticancer Activity of Pyrrolidine Dithiocarbamate-Copper Complex against Cisplatin-resistant Neuroblastoma Cells. Anti-cancer Drugs, 2008; 19(2):125-132. PMID: 18176108

20. Rodriguez VR, Joshi A, Peng F, Rabah RM, Stockmann PT, Savaşan S. Positron emission tomography in subcutaneous panniculitis-like T-cell lymphoma. Pediatr Blood Cancer. 2009;52:406–408. PMID: 18985722

21. Juhász C, Muzik O, Lu X, Jahania MS, Soubani AO, Khalaf M, Peng F, Mangner TJ, Chakraborty PK, Chugani DC. Quantification of tryptophan transport and metabolism in lung tumors using positron emission tomography. J. Nucl Med, 2009; 50(3): 356-363. PMID: 19223408

22. Peng, F, Lutsenko S, Sun X, Muzik O. Positron Emission Tomography of Copper Metabolism in the Atp7b -/- Knock-out Mouse Model of Wilson’s Disease. Mol Imaging and Biology, 2011, Epub ahead of print. DOI: 10.1007/s11307-011-0476-4 PMID: 21327972.

23. Zhang, H, Cai, H., Lu, X, Muzik, O., Peng, F. Positron Emission Tomography of Human Hepatocellular Carcinoma Xenografts in Mice using Copper (II)-64 Chloride as a tracer. Academic Radiology, 2011 (In press)

 


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