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夏江教授学术报告(2012-06-17)

( 2012-06-15 )
 

报告题目

Protein designing and architecting: applications in surface biochemistry and protein labeling

报告时间

2012617 (星期日) 上午10:00

报告地点

材料楼五楼会议室

报告人

Prof. Xia Jiang (夏江),香港中文大学化学系

 
Assistant Professor

Education
1999 B.S. Nanjing University
2002 M.S. Nanjing University
2006 Ph.D.
Stanford University

Positions Held
2007 – 2008 Postdoctoral scholar, California Institute of Technology
2007 – 2008 Research Associate, Howard Hughes Medical Institute
2009 – present Assistant Professor, the Chinese University of Hong Kong

Research Interests

Physical biochemistry, bioorganic chemistry, and chemical biology

Representative Publications
1. Wang, J.†; Jiang, P.†; Han, Z.; Qiu, L.; Wang, C.; Zheng, Bo.; Xia, J.*
“Fast Self-assembly Kinetics of Quantum Dots and a Dendrimeric Peptide Ligand”
Langmuir, DOI: 10.1021/la301227r. (†equal contribution)
2. Wang, J.†; Jin, X.†; Liu, J.; Khosla, C.*; Xia, J. *
“Resolving multiple protein-peptide binding events: implication for HLA-DQ2 mediated antigen presentation in celiac disease”
Chemistry – An Asian Journal, 2012, 7, 992-999. (†equal contribution)
Featured in Chemistry Views: http://www.chemistryviews.org/details/ezine/1576983/Gluten_Breakdown.html
3. Brown, J. M.†; Xia, J.†; Zhuang, B.; Cho, K-S.; Rogers, C. J.; Gama, C. I.; Rawat, M.; Tully, S.E.; Uetani, N.; Mason, D.; Tremblay, M. L.; Peter, E.C.; Habuchi, O.; Chen, D.F.; Hsieh-Wilson, L.C.
“A Sulfated Carbohydrate Epitope Inhibits Axon Regeneration After Injury”,
Proc. Nat. Acad. Sci., 2012, 109, 4768-4773. (†equal contribution)
4. Wang, J.; Xia, J.*
“Capillary Electrophoretic Studies on Displacement and Proteolytic Cleavage of Surface Bound Oligohistidine Peptide on Quantum Dots”
Analytica Chimica Acta, 2012, 709, 120-127.
5. Wang, J.; Xia, J.*
“Preferential Binding of a Novel Polyhistidine Peptide Dendrimer Ligand on Quantum Dots Probed by Capillary Electrophoresis”
Analytical Chemistry, 2011, 83, 6323-9.
6. Wang, J.; Yue, Y.; Chen, G.; Xia, J.*
“Protease-Promoted Drug Delivery Using Peptide-Functionalized Gold Nanoparticles”
Soft Matter, 2011, 7, 7217-7222.
7. Luo, S.*; Ling, C.; Hu, X.; Liu, X.; Chen, S.; Han, M.; Xia, J. “Thermoresponsive unimolecular micelles with a hydrophobic dendritic core and a double hydrophilic block copolymer shell”
Journal of Colloid and Interface Science, 2011, 353, 76-82.
8. Siegel, M.†; Xia, J.†; Khosla, C.
“Structure-based design of α-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2”
Bioorganic and Medicinal Chemistry, 2007, 15(18), 6253-61 (†equal contribution)
9. Xia, J.†; Bergseng, E.†; Siegel, M.; Fleckenstein, B.; Kim, C. Y.; Sollid, L.M.; Khosla, C.
"Cyclic and Dimeric Gluten Peptide Analogues to Inhibit DQ2-Mediated Antigen Presentation in Celiac Disease"
Bioorganic and Medicinal Chemistry, 2007, 15(20), 6565-73. (†equal contribution)
10. Xia, J. ; Siegel, M.; Bergseng, E.; Sollid, L. M.; Khosla, C.
“Inhibition of HLA-DQ2 mediated antigen presentation by analogues of a high affinity 33-residue peptide from a2-Gliadin”
Journal of the American Chemical Society, 2006, 128(6), 1859-67.

 
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